β-Pinene Derived Products With Enhanced In Vitro Antimicrobial Activity

The development of new antimicrobials has always been a research hotspot. In this study, β-pinene-based derivatives were synthesized, and their antimicrobial activity was evaluated. purpose to develop some novel, promising fungicides. Three β-pinene containing bis-hydronopyl prepared, antifungal antibacterial activities evaluated against 6 plant pathogenic fungi 4 bacterial species; preliminary structure-activity relationship is discussed. results indicated that the blend alkyl group had potent inhibitory fungal pathogens bacteria. Among these molecules, dimethyl ammonium bromide showed excellent effects on Colletotrichum acutatum with half-maximal effective concentration 0.538 µg/mL, which lower than carbendazim. Scanning electron microscope after administration (compound 3a), C. mycelia sunken deformed in comparison control group. Furthermore, methyl better those ethyl derivatives. These provide insights into inhibition bacteria by derivatives, may lead them be used as precursor molecules for novel pesticides further research.